| A-1 Development, Old Highway 67 Commercial Development Woolmarket | Water Quality - 401 Certification | Biloxi | Harrison |
| AC Polymers Inc | Air - SMOP Modification | Byhalia | Marshall |
| AMJI Investment Group, LLC, Olive Branch RV Park | Water Quality - 401 Certification | Olive Branch | Desoto |
| APAC Mississippi Inc, Guntown Asphalt Plant | Water - State Operating Permit Renewal | Guntown | Lee |
| ATM Holdings, LLC, Legacy Medical Park | Water Quality - 401 Certification | Gautier | Jackson |
| Aberdeen POTW, East | Water - NPDES Major Municipal Renewal | Aberdeen | Monroe |
| Acme Oil Recycling, LLC | Water - Pretreatment | Poplarville | Pearl River |
| Adams County WWTF | Water - NPDES Minor Industrial Renewal | Natchez | Adams |
| Affiliated Computer Services, DBA, Conduent Business Services, LLC | Water - State Operating Permit Renewal | Flora | Madison |
| Agricultural Research Service, Alluvial Aquifer Recharge Project | Water - NPDES Minor Industrial Renewal | Shellmound | Leflore |
| Air Care Flying LLC | Water - State Operating Permit Renewal | Yazoo City | Yazoo |
| Akers Railroad Holdings, LLC, Chipper Yard | Air - Construction Permit Modification | Amory | Monroe |
| Alcorn County Schools, Biggersville School | Water - NPDES Commercial Renewal | Corinth | Alcorn |
| Alcorn State University | Water - NPDES Minor Municipal Renewal | Alcorn State | Claiborne |
| Alcorn State University at Church Hill | Water - State Operating Permit Renewal | Fayette | Jefferson |
| Allen Creek Resort Inc | Water - State Operating Permit Renewal | Brandon | Rankin |
| Alpek Polyester Mississippi Inc | Air - Title V Admin Mod | Bay St. Louis | Hancock |
| Alpek Polyester Mississippi Inc | Water - NPDES Minor Industrial Admin Mod | Bay St. Louis | Hancock |
| Alpek Polyester Mississippi Inc | Water - Pretreatment ADMIN | Bay St. Louis | Hancock |
| Alter Trading Corporation - Sardis | Air - SMOP | Sardis | Panola |
| Aluminum Dynamics, LLC | Water - NPDES Minor Industrial | Columbus | Lowndes |
| Ambassador Holdings LLC, Reservoir Ridge Mobile Home Park | Water - NPDES Commercial Admin Mod | Waynesboro | Wayne |
| Ambit Chemical Technologies | Water - NPDES Minor Industrial Admin Mod | Gulfport | Harrison |
| Amick Farms LLC | Air - SMOP Modification | Laurel | Jones |
| Amick Farms LLC, Laurel Processing Plant | Water - Pretreatment Renewal | Laurel | Jones |
| April Jones, Holly Ridge Development | Water - NPDES Commercial Renewal | Vicksburg | Warren |
| Arcola POTW | Water - NPDES Minor Municipal Renewal | Arcola | Washington |
| Ardagh Metal Packaging USA Corp | Water - Pretreatment Renewal | Olive Branch | Desoto |
| Auburn Apartments LLC, Guru Properties | Water - NPDES Commercial Renewal | Tupelo | Lee |
| Aviation Flying Service Inc | Water - State Operating Permit Renewal | Sidon | Leflore |
| Avon Engineered Fabrications Inc | Air - Title V Renewal | Picayune | Pearl River |
| B Karen Galey, B and K Mobile Home Park | Water - NPDES Commercial Renewal | Vicksburg | Warren |
| Bakers Ready Mix and Construction, LLC, Louisville Brick Company | Water Quality - 401 Certification | Louisville | Winston |
| Bart Edmiston, Tomaston Medical Center | Water Quality - 401 Certification | Biloxi | Harrison |
| Baxter Healthcare Corporation | Air - SMOP Modification | Cleveland | Bolivar |
| Bay Springs Industrial Park | Water - NPDES Minor Industrial Renewal | Bay Springs | Jasper |
| Bay Springs POTW | Water - NPDES Minor Municipal Renewal | Bay Springs | Jasper |
| Bayer Research and Development Services LLC | Water - NPDES Minor Industrial Renewal | Scott | Bolivar |
| Beatriz and Crosofo Duarte, Red Hill Mobile Home Park | Water - NPDES Commercial Admin Mod | Batesville | Panola |
| Behold Washington LLC, Behold Home-Amory | Air - Construction Permit | Amory | Monroe |
| Berryhill Trailer Park LLC | Water - NPDES Commercial Renewal | Lyon | Coahoma |
| Best Foam Inc | Air - SMOP Renewal | Sherman | Pontotoc |
| Blane Davis dba Country Farms Quail | Water - State Operating Permit Renewal | Lucedale | George |
| Blue Mountain College, South Campus | Water - State Operating Permit Renewal | Blue Mountain | Tippah |
| BlueScope Coated Products LLC | Water - Pretreatment Renewal | Jackson | Hinds |
| Bobby Haygood, Mill Creek Condominiums | Water - State Operating Permit Renewal | Iuka | Tishomingo |
| Bobby Pennington, Crows Neck RV Campground | Water - State Operating Permit Renewal | Tishomingo | Tishomingo |
| Bollinger Gulfport Shipbuilding, LLC | Air - Title V Admin Mod | Gulfport | Harrison |
| Bollinger Mississippi Repair, LLC | Air - Title V Minor Modification | Pascagoula | Jackson |
| Boswell Regional Center | Water - NPDES Commercial Renewal | Magee | Simpson |
| Bridgewater Utilities Inc, Bridgewater Subdivision | Water - NPDES Commercial Renewal | Ellisville | Jones |
| Brignac Flying Service LLC | Water - State Operating Permit Renewal | Columbus | Lowndes |
| Brookhaven Pellets LLC | Air - Title V | Brookhaven | Lincoln |
| Brooksville POTW | Water - NPDES Minor Municipal Renewal | Brooksville | Noxubee |
| Buddys Automotive LLC | Water - State Operating Permit Renewal | Collins | Covington |
| Bude POTW | Water - NPDES Minor Municipal Renewal | Bude | Franklin |
| Burns and Burns Inc, Centerhill Sunoco Number 28 | Water - NPDES Commercial Renewal | Meridian | Lauderdale |
| Byhalia POTW | Water - NPDES Minor Municipal Renewal | Byhalia | Marshall |
| CF Industries Nitrogen LLC | Air - Title V Minor Modification | Yazoo City | Yazoo |
| CPP LLC | Water - State Operating Permit Renewal | Picayune | Pearl River |
| Calgon Carbon Corporation | Water - Pretreatment Renewal | Bay St. Louis | Hancock |
| Calhoun City POTW | Water - NPDES Minor Municipal Renewal | Calhoun City | Calhoun |
| CamDav, LLC, Highway 49 Storage Facility | Water Quality - 401 Certification | Gulfport | Harrison |
| CamDav, LLC, Highway 49 Storage Facility | Water Quality - 401 Certification | Gulfport | Harrison |
| Cane Creek Properties LLC | Water - NPDES Commercial Renewal | Corinth | Alcorn |
| Canton Municipal Utilities | Air - Title V Renewal | Canton | Madison |
| Carroll County Board of Supervisors, County Courthouse Project | Water - NPDES Commercial Renewal | Carrollton | Carroll |
| Carthage POTW | Water - NPDES Minor Municipal Renewal | Carthage | Leake |
| Caswell Springs United Methodist Church | Water - State Operating Permit Renewal | Moss Point | Jackson |
| Cavenham Forest Industries LLC, Lyman Site One | Water - NPDES Minor Industrial Renewal | Lyman | Harrison |
| Cavenham Forest Industries LLC, Lyman Site Two | Water - NPDES Minor Industrial Renewal | Lyman | Harrison |
| Cayce 302, LLC, Convenience Store and Gas Station | Water Quality - 401 Certification | Byhalia | Marshall |
| Central Mississippi Cremation Services | Air - Construction Permit | Morton | Scott |
| Charles Lee Circle LLC, Serena Park | Water - NPDES Commercial Renewal | Hattiesburg | Lamar |
| Charleston POTW | Water - NPDES Minor Municipal Renewal | Charleston | Tallahatchie |
| Chemours Company FC LLC The, Delisle Plant | Air - Title V Renewal | Pass Christian | Harrison |
| Chevron USA, Inc, DBA Chevron Products Company, Collins Terminal | Water - State Operating Permit Renewal | Collins | Covington |
| Chevron USA, Inc, DBA Chevron Products Company, Collins Terminal | Water - NPDES Minor Industrial Renewal | Collins | Covington |
| Chris Martin dba The Car Wash | Water - State Operating Permit Renewal | Perkinston | Hancock |
| Christian Fellowship Retreat at Crows Neck | Water - NPDES Commercial, NPDES Federal Minor Renewal | Tishomingo | Tishomingo |
| Christmas Flying Service, LLC | Water - State Operating Permit Renewal | Shelby | Bolivar |
| Church of God The Bibleway Inc, Indian Springs Campground | Water - NPDES Commercial Renewal | Kosciusko | Attala |
| City of Hattiesburg, Lincoln Road Stormwater Detention Facility | Water Quality - 401 Certification | Hattiesburg | Forrest |
| Claiborne County Public Schools, Claiborne County High School and Vo Tech Center | Water - NPDES Commercial Renewal | Port Gibson | Claiborne |
| Clarkdale Villas LLC | Water - NPDES Commercial Renewal | Meridian | Lauderdale |
| Clinton POTW, Southside | Water - NPDES Major Municipal Renewal | Clinton | Hinds |
| Cock of the Walk Hwy 49 LLC | Water - NPDES Commercial Renewal | Jackson | Hinds |
| Columbia POTW, South | Water - NPDES Major Municipal Renewal | Columbia | Marion |
| Columbus Marble Works Inc | Water - State Operating Permit Renewal | Columbus | Lowndes |
| Composite Building Systems Inc (OOB) | Air - Title V Renewal | Paden | Tishomingo |
| Confortaire Inc | Air - SMOP Renewal | Tupelo | Lee |
| Cooperative Energy, a Mississippi electric cooperative, Benndale Peaking Station | Air - SMOP Modification | Benndale | George |
| Cooperative Energy, a Mississippi electric cooperative, Moselle Generating Plant | Air - Title V Renewal | Moselle | Jones |
| Copiah County Industrial Park | Water - NPDES Minor Industrial, NPDES Minor Municipal Renewal | Gallman | Copiah |
| Copperfield Subdivision | Water Quality - 401 Certification | Hattiesburg | Lamar |
| Corinth Gas and Water, Corinth Drinking Treatment Plant | Water - NPDES Minor Industrial Renewal | Corinth | Alcorn |
| Corinth POTW | Water - NPDES Major Municipal Renewal | Corinth | Alcorn |
| Crawford POTW | Water - NPDES Minor Municipal Renewal | Crawford | Lowndes |
| Creative Kids Inc | Water - State Operating Permit Renewal | Hattiesburg | Lamar |
| Custom Air LLC | Water - State Operating Permit Renewal | Louisville | Winston |
| DeSoto County Regional Utility Authority, Braybourne Subdivision | Water - NPDES Minor Municipal Renewal | Olive Branch | Desoto |
| DeSoto County Regional Utility Authority, Metro DeSoto WWTP | Water - NPDES Major Municipal Renewal | Olive Branch | Desoto |
| Dealers Auto Auction of Jackson, LLC | Water - NPDES Commercial Renewal | Pearl | Rankin |
| Deepwell Energy Services, LLC, Waynesboro | Water - NPDES Minor Industrial Renewal | Waynesboro | Wayne |
| Delta Dusters II LLC | Water - State Operating Permit | Tunica | Tunica |
| Denbury Onshore LLC, Mallalieu EOR Facility | Water - NPDES Minor Industrial Renewal | Bogue Chitto | Lincoln |
| Derma POTW | Water - NPDES Minor Municipal Renewal | Derma | Calhoun |
| Diamond S Farms Inc | Water - NPDES Minor Industrial Renewal | Maben | Choctaw |
| Diamondhead Water and Sewer District | Water - NPDES Major Municipal Modification | Diamondhead | Hancock |
| Discovery Energy LLC, Engine Plant Number 1 | Air - SMOP Admin Mod | Hattiesburg | Forrest |
| Discovery Energy LLC, Engine Plant Number 1 | Water - State Operating Permit Admin Mod | Hattiesburg | Forrest |
| Discovery Energy LLC, Engine Plant Number 2 | Air - Title V Admin Mod | Hattiesburg | Forrest |
| Discovery Energy LLC, Engine Plant Number 2 | Air - Title V Modification | Hattiesburg | Forrest |
| Doddsville POTW | Water - NPDES Minor Municipal Renewal | Doddsville | Sunflower |
| Double C Feed & Seed Store LLC | Water - NPDES Commercial Renewal | Carthage | Leake |
| Double D, LLC, Ocean Springs Baseball Training Facility | Water Quality - 401 Certification | Ocean Springs | Jackson |
| Duck Hill POTW | Water - NPDES Minor Municipal Renewal | Duck Hill | Montgomery |
| E.E. Pickle Funeral Home Inc, Cremation Center | Air - Construction Permit | Smithville | Monroe |
| EP Engineered Clays Corporation | Air - Title V Minor Modification | Jackson | Hinds |
| Entergy Mississippi LLC, Gerald Andrus Plant | Water - NPDES Major Industrial Renewal | Greenville | Washington |
| Entergy Mississippi LLC, Hinds County Plant | Water - Pretreatment Renewal | Jackson | Hinds |
| Enviva Pellets Amory LLC | Air - Title V Modification | Amory | Monroe |
| Enviva Pellets Bond, LLC | Air - Construction Admin Mod | Wiggins | Stone |
| Enviva Port of Pascagoula LLC | Air - Construction Permit Modification | Pascagoula | Jackson |
| Ergon Refining Inc | Water - NPDES Minor Industrial Renewal | Vicksburg | Warren |
| Evonne Sanford, Prospect Trailer Park | Water - NPDES Commercial Renewal | Richton | Perry |
| Exxon Mobil Corporation, Centreville Landfarm | Water - NPDES Minor Industrial Renewal | Centreville | Wilkinson |
| FXI Inc, Coldwater | Air - SMOP Renewal | Coldwater | Tate |
| Fairbanks Scales Inc | Air - SMOP Modification | Meridian | Lauderdale |
| Faith Baptist Church | Water - NPDES Commercial Renewal | Meridian | Lauderdale |
| First Presbyterian Church of Jackson, Mississippi, Twin Lakes Conference Center | Water - NPDES Commercial Renewal | Florence | Rankin |
| Florence POTW | Water - NPDES Minor Municipal Renewal | Florence | Rankin |
| Florida Gas Transmission Company LLC, Wiggins Compressor Station Number 10 | Air - Title V Minor Modification | Wiggins | Perry |
| Fluent by Voyant Beauty | Water - Pretreatment Renewal | Olive Branch | Desoto |
| Foamcraft Inc | Air - SMOP Renewal | Tupelo | Lee |
| Forest Industrial Wastewater Pretreatment Inc | Water - Pretreatment Renewal | Forest | Scott |
| Fountain of Life Tabernacle Church | Water - NPDES Commercial Renewal | Gulfport | Harrison |
| Friends of Children of Mississippi Inc, Riven Oaks Headstart Center | Water - NPDES Commercial Renewal | Silver City | Humphreys |
| Frog Hollow RV Park LLC | Water - State Operating Permit Renewal | Grenada | Grenada |
| Fulton POTW, South | Water - NPDES Minor Municipal Renewal | Fulton | Itawamba |
| Future Foam Inc | Air - SMOP Renewal | Tupelo | Lee |
| G3 Flying LLC | Water - State Operating Permit Renewal | Lambert | Quitman |
| GPS Land Company LLC, Mobile Home Park | Water - NPDES Commercial Renewal | Florence | Rankin |
| Genesis Rail Services LLC, Natchez Terminal | Air - SMOP Renewal | Natchez | Adams |
| Georgia Pacific Wood Products LLC, Taylorsville | Air - Title V Modification | Taylorsville | Smith |
| Girl Scouts Heart of the South, Camp Tik A Witha | Water - NPDES Commercial Renewal | Van Vleet | Chickasaw |
| Glendale Utility District | Water - NPDES Minor Municipal Renewal | Hattiesburg | Forrest |
| Glenn Dale White, Northwood Mobile Home Park | Water - NPDES Commercial Renewal | Vicksburg | Warren |
| Gloster Forest Products, LLC | Water - Pretreatment | Gloster | Amite |
| Gloster POTW | Water - NPDES Minor Municipal Modification | Gloster | Amite |
| Golden Triangle Regional Solid Waste Management Authority | Water - Pretreatment Renewal | Starkville | Oktibbeha |
| Golden Triangle Regional Solid Waste Management Authority | Water - NPDES Storm Renewal | Starkville | Oktibbeha |
| Grace POTW | Water - NPDES Minor Municipal Renewal | Grace | Issaquena |
| Great River Utiility Operating Company LLC, The Villages | Water - State Operating Permit Admin Mod | Hattiesburg | Lamar |
| Great River Utility Company LLC, Brookwood Place Subdivision | Water - NPDES Commercial Renewal | Vicksburg | Warren |
| Great River Utility Company LLC, Lake Village Estates Northridge and Windance | Water - NPDES Commercial Admin Mod | Gulfport | Harrison |
| Great River Utility Operating Company LLC, Oakdale Park Subdivision | Water - NPDES Commercial Renewal | Columbus | Lowndes |
| Great River Utility Operating Company LLC, Black Creek Utilities | Water - State Operating Permit Renewal | Hattiesburg | Forrest |
| Great River Utility Operating Company LLC, Cypress Creek Plantation | Water - NPDES Commercial Renewal | Olive Branch | Desoto |
| Great River Utility Operating Company LLC, Fairways Subdivision | Water - NPDES Commercial Renewal | Vicksburg | Warren |
| Great River Utility Operating Company LLC, Grove Development, The | Water - NPDES Commercial Admin Mod | Vicksburg | Warren |
| Great River Utility Operating Company LLC, Hillcrest Subdivision | Water - NPDES Commercial Renewal | Columbus | Lowndes |
| Great River Utility Operating Company LLC, Hollyrood and Trace Hills Subdivision | Water - NPDES Commercial Renewal | Port Gibson | Claiborne |
| Great River Utility Operating Company LLC, Hollyrood and Trace Hills Subdivision | Water - NPDES Commercial Admin Mod | Port Gibson | Claiborne |
| Great River Utility Operating Company LLC, Hughes Estates Subdivision | Water - NPDES Commercial Renewal | Columbus | Lowndes |
| Great River Utility Operating Company LLC, Kerry Estates, New Hope Garden Apartments | Water - NPDES Commercial Renewal | Columbus | Lowndes |
| Great River Utility Operating Company LLC, Lakes of Oxford, The | Water - NPDES Commercial Renewal | Oxford | Lafayette |
| Great River Utility Operating Company LLC, New Hope Park Subdivision | Water - NPDES Commercial Renewal | Columbus | Lowndes |
| Great River Utility Operating Company LLC, Openwood Plantation | Water - NPDES Commercial Renewal | Vicksburg | Warren |
| Great River Utility Operating Company LLC, Ridge Park, Wakeland Hills and Wildwood Subdivisions | Water - NPDES Commercial Renewal | Raymond | Hinds |
| Great River Utility Operating Company LLC, Rolling Hills Subdivision | Water - NPDES Commercial Renewal | Florence | Rankin |
| Great River Utility Operating Company LLC, Shelby Place of Oxford | Water - NPDES Commercial Renewal | Oxford | Lafayette |
| Great River Utility Operating Company LLC, Twelve Oaks Estates Subdivision | Water - NPDES Commercial Renewal | Oxford | Lafayette |
| Great River Utility Operating Company LLC, Windridge Subdivision | Water - NPDES Commercial Renewal | Hattiesburg | Lamar |
| Great River Utility Operating Company LLC, Woodland Acres Subdivision | Water - NPDES Commercial Renewal | Florence | Rankin |
| Great River Utility Operating Company, LLC, Greenbriar Subdivision | Water - NPDES Commercial Admin Mod | Vicksburg | Warren |
| Great River Utility Operating Company, LLC, Oak Grove Subdivision and Oak Grove Townhouses | Water - NPDES Commercial Renewal | Oak Grove | Lamar |
| Great River Utility Operating Company, LLC, Seneca Hills Subdivision | Water - NPDES Commercial Renewal | Vancleave | Jackson |
| Great River Utility Operating Company, LLC, Serene Hills Subdivision | Water - NPDES Commercial Renewal | Hattiesburg | Forrest |
| Grenada Stamping and Assembly Inc | Water - Pretreatment Renewal | Grenada | Grenada |
| Gulf Pride Enterprises Inc | Water - NPDES Minor Industrial Renewal | Biloxi | Harrison |
| Gulf Pride Enterprises Inc, Plant Number 2 | Water - NPDES Minor Industrial Renewal | Biloxi | Harrison |
| Gulf South Pipeline Company LLC, Petal Compressor Station | Air - Title V Renewal | Petal | Forrest |
| Gulf South Pipeline Company, LLC Jackson Compressor Station | Air - Title V Renewal | Flowood | Rankin |
| H F T Holdings LLC, Oak Place Apartments | Water - State Operating Permit Renewal | Hattiesburg | Lamar |
| H M Richards Inc | Air - SMOP Renewal | Guntown | Lee |
| Hancock County Board of Supervisors, Bayou Caddy Marina | Water Quality - 401 Certification | Lakeshore | Hancock |
| Hancock County Utility Authority, Northern Regional WWTP | Water - NPDES Major Municipal Renewal | Kiln | Hancock |
| Hancock County Utility Authority, Oak Harbor Subdivision | Water - NPDES Commercial Renewal | Pearlington | Hancock |
| Hancock County Utility Authority, Oak Harbor Subdivision | Water - NPDES Commercial Admin Mod | Pearlington | Hancock |
| Haney Properties LP | Water - NPDES Commercial Renewal | Pearl | Rankin |
| Hardy Technologies LLC | Water - Pretreatment Modification | Lumberton | Lamar |
| Hardy Technologies LLC | Air - Construction PSD modification | Lumberton | Lamar |
| Harrison County School District, Harrison Central High School | Water - NPDES Commercial Renewal | Gulfport | Harrison |
| Harrison County School District, Lizana Elementary School | Water - NPDES Commercial Renewal | Gulfport | Harrison |
| Harrison County School District, Saucier Elementary School | Water - NPDES Commercial Renewal | Saucier | Harrison |
| Harrison County Utility Authority, East Biloxi POTW | Water - NPDES Major Municipal Renewal | Biloxi | Harrison |
| Harrison County Utility Authority, Riverhills Wastewater Treatment Facility | Water - NPDES Minor Municipal Renewal | Gulfport | Harrison |
| Harrison County Utility Authority, S20 D Iberville WWTF and Transmission System | Water - NPDES Major Municipal Renewal | D'Iberville | Harrison |
| Harrison County Utility Authority, South Woolmarket WRRF | Water - NPDES Major Municipal Renewal | Woolmarket | Harrison |
| Hawley's Carwash LLC | Water - NPDES Commercial Renewal | Bude | Franklin |
| Heartland Catfish Company Inc | Water - NPDES Minor Industrial Renewal | Itta Bena | Leflore |
| Hegwood Mobile Home Community | Water - NPDES Commercial Renewal | Oak Grove | Lamar |
| Heidelberg POTW | Water - NPDES Minor Municipal Renewal | Heidelberg | Jasper |
| Hills of the Bear Homeowners Association Inc, Hills of the Bear Subdivision | Water - State Operating Permit Renewal | Iuka | Tishomingo |
| Hinds County Human Resource Agency, Welcome Head Start Center | Water - NPDES Commercial Renewal | Utica | Hinds |
| Hinds County School District, Bolton Edwards School | Water - NPDES Commercial Renewal | Bolton | Hinds |
| Hinds County School District, Gary Road Elementary | Water - NPDES Commercial Renewal | Byram | Hinds |
| Hitachi Energy USA Inc | Air - SMOP Admin Mod | Crystal Springs | Copiah |
| Holcomb Aerial Services Inc | Water - State Operating Permit Renewal | Flora | Madison |
| Holly Springs POTW, Number 1 | Water - NPDES Minor Municipal Renewal | Holly Springs | Marshall |
| Hood Industries Inc | Air - Title V Modification | Silver Creek | Lawrence |
| Hood Industries Inc, Waynesboro | Air - Title V Renewal | Waynesboro | Wayne |
| Howard Industries Inc | Water - NPDES Minor Industrial Renewal | Mendenhall | Simpson |
| Huber Engineered Woods, LLC | Air - Construction Permit | Shuqualak | Noxubee |
| Humphreys Academy Foundation, Humphreys Academy | Water - NPDES Commercial Renewal | Belzoni | Humphreys |
| Hunter Douglas Window Coverings, Inc. | Water - Pretreatment Renewal | Shannon | Lee |
| Hunter Engineering Company, Raymond | Water - Pretreatment Modification | Raymond | Hinds |
| ITT Engineered Valves LLC | Air - SMOP Modification | Amory | Monroe |
| Ibrahams Real Estate Holding as Joe Joes Travel Center | Water - NPDES Commercial Renewal | Red Banks | Marshall |
| Interfor US Inc, Bay Springs Division | Air - Title V Renewal | Bay Springs | Jasper |
| International Paper Company, Magnolia Facility | Air - SMOP | Magnolia | Pike |
| International Paper Company, Olive Branch | Air - SMOP | Olive Branch | Desoto |
| International Paper Company, Richland Facility | Water - Pretreatment Renewal | Richland | Rankin |
| International Paper Company, Richland Facility | Air - SMOP Renewal | Richland | Rankin |
| International Paper Company, Vicksburg Mill | Air - Title V Modification | Redwood | Warren |
| Isola POTW | Water - NPDES Minor Municipal Renewal | Isola | Humphreys |
| J M J Rentals LLC, Lamar Pines Mobile Home Community | Water - State Operating Permit Renewal | Purvis | Lamar |
| J Strickland and Company, Manufacturing Plant | Water - Pretreatment | Olive Branch | Desoto |
| JP Oil Company LLC, Lake Como Field | Air - Title V Admin Mod | Bay Springs | Jasper |
| JS LLC, Heard Town Estates Subdivision | Water - NPDES Commercial Renewal | Tupelo | Lee |
| Jackson County Board of Supervisors, Greenfields Road Project | Water Quality - 401 Certification | Moss Point | Jackson |
| Jackson County Port Authority, Black Creek Cooling Water Facility | Water - NPDES Minor Industrial Renewal | Escatawpa | Jackson |
| Jackson County Port Authority, Dredging Bayou Casotte | Water Quality - 401 Certification | Pascagoula | Jackson |
| Jackson County Utility Authority POTW 3D | Water - State Operating Permit Renewal | Lucedale | Jackson |
| Jackson County Utility Authority, JCUA POTW 5D | Water - State Operating Permit Renewal | Moss Point | Jackson |
| Jackson POTW, Presidential Hills | Water - NPDES Minor Municipal Renewal | Jackson | Hinds |
| Jamie Whitten Delta States Research Center | Water - NPDES Minor Industrial Renewal | Stoneville | Washington |
| Jetsetter Gardenia Hill LLC | Water - NPDES Commercial Renewal | Perkinston | Stone |
| Jindal Tubular USA LLC | Air - SMOP Renewal | Bay St. Louis | Hancock |
| Jolimar Summit Fitness Retreat | Water - NPDES Commercial Renewal | Summit | Lincoln |
| Jones County School District, Sharon Elementary School | Water - NPDES Commercial Renewal | Laurel | Jones |
| Jones County School District, West Jones Elementary | Water - NPDES Commercial Renewal | Laurel | Jones |
| Jonestown POTW | Water - NPDES Minor Municipal Renewal | Jonestown | Coahoma |
| Julie R. Saucier dba Stevens Packing Company | Water - State Operating Permit Renewal | Poplarville | Pearl River |
| K L M Enterprises LLC dba Highway 49 Flea Market | Water - State Operating Permit Renewal | Hattiesburg | Forrest |
| Kace Properties LLC, Cabins at Oktoc | Water - State Operating Permit | Starkville | Oktibbeha |
| Kanes Korner LLC, Kanes Catfish, Seafood and Steakhouse | Water - State Operating Permit Renewal | Foxworth | Marion |
| Kansas City Southern Railway Company | Water - NPDES Minor Industrial Renewal | Artesia | Lowndes |
| Kathy Whitehead dba Cowboy Jims | Water - NPDES Commercial Renewal | Prentiss | Covington |
| Katsib Properties LLC, Smith Mobile Home Park | Water - NPDES Commercial Renewal | Batesville | Panola |
| Keith Lee dba Dollys Quic Stop | Water - State Operating Permit Renewal | Kiln | Hancock |
| Kenney Property Holdings LLC, Verona Truck Service Center | Water - State Operating Permit Renewal | Shannon | Lee |
| Kentucky Tennessee Clay Company, Sledge | Air - Title V Renewal | Crenshaw | Quitman |
| Kings Packing Company LLC | Water - State Operating Permit | Summit | Pike |
| Kirk Padgett, Flint Creek Manor | Water - State Operating Permit Renewal | Wiggins | Stone |
| Koppers Inc Mathiston Pole Drying Facility | Air - Construction Admin Mod | Mathiston | Choctaw |
| LNJ Services Inc | Water - Pretreatment | Gulfport | Harrison |
| Lafayette County Industrial Park | Water - NPDES Minor Industrial Renewal | Oxford | Lafayette |
| Lake Forest Ranch Inc, Lake Forest Ranch Camp | Water - NPDES Commercial Renewal | Macon | Noxubee |
| Lake POTW | Water - NPDES Minor Municipal Renewal | Lake | Scott |
| Lakecrest Condominium Inc | Water - State Operating Permit Renewal | Iuka | Tishomingo |
| Lampton Sewer District POTW | Water - NPDES Minor Municipal Renewal | Columbia | Marion |
| Lauderdale County School District, Clarksdale Attendance Center | Water - NPDES Commercial Renewal | Meridian | Lauderdale |
| Lauderdale County School District, Northeast High School | Water - NPDES Commercial Renewal | Meridian | Lauderdale |
| Lauderdale County School District, Southeast High School | Water - NPDES Commercial Renewal | Meridian | Lauderdale |
| Lauderdale County School District, West Lauderdale Elementary School | Water - State Operating Permit Renewal | Meridian | Lauderdale |
| Leake County Board of Education, Edinburg Attendance Center | Water - NPDES Commercial Renewal | Edinburg | Leake |
| Leake County Board of Education, Thomastown Attendance Center | Water - NPDES Commercial Renewal | Thomastown | Leake |
| Legacy Boats LLC dba Avid Boats | Air - Construction Permit | Aberdeen | Monroe |
| Louise POTW | Water - NPDES Minor Municipal Renewal | Louise | Humphreys |
| Louisville, City of, City of Louisville Solid Waste Landfill | Water - NPDES Storm Renewal | Louisville | Winston |
| Lowndes County School District, West Lowndes Elementary School | Water - NPDES Commercial Renewal | Columbus | Lowndes |
| Lumberton POTW | Water - NPDES Minor Municipal Renewal | Lumberton | Lamar |
| M J Feed Mill MS, LLC | Air - Construction Permit | New Augusta | Perry |
| MDOT, Delma Furness Hospitality Station | Water - NPDES Commercial Renewal | Lula | Coahoma |
| MDOT, Interstate 10, Welcome Center, Hancock | Water - NPDES Commercial Renewal | Pearlington | Hancock |
| MDOT, Interstate 55 North, Rest Area, Panola | Water - NPDES Commercial Renewal | Courtland | Panola |
| MDOT, Interstate 55 South, Rest Area, Panola | Water - NPDES Commercial Renewal | Batesville | Panola |
| MDOT, Leake County Maintenance Headquarters | Water - NPDES Commercial Renewal | Carthage | Leake |
| MDOT, Scott County Maintenance Headquarters | Water - NPDES Commercial Renewal | Morton | Scott |
| MGC Terminal LLC | Water - NPDES Minor Industrial Renewal | Meridian | Lauderdale |
| MGC Terminal LLC | Water - State Operating Permit | Meridian | Lauderdale |
| MSARNG, AVCRAD | Air - SMOP Modification | Gulfport | Harrison |
| Maben POTW | Water - NPDES Minor Municipal Renewal | Maben | Webster |
| Macon POTW | Water - NPDES Minor Municipal Renewal | Macon | Noxubee |
| Madison County School District, Luther Branson Elementary School | Water - NPDES Commercial Renewal | Canton | Madison |
| Madison County School District, Velma Jackson School | Water - NPDES Commercial Renewal | Camden | Madison |
| Madison South Rubbish Land Fill Inc | Water - NPDES Storm Renewal | Ridgeland | Madison |
| Madison South Rubbish Land Fill Inc | Solid Waste - Rubbish Renewal | Ridgeland | Madison |
| Maintenance Systems Inc Boyd Site | Solid Waste - Land Application | Lena | Leake |
| Maintenance Systems Inc Cliburn Site | Solid Waste - Land Application | Florence | Rankin |
| Manheim Remarketing Inc, Manheim Mississippi | Water - State Operating Permit Renewal | Hattiesburg | Forrest |
| Manoj Bajaj dba Eds Quickie | Water - NPDES Commercial Renewal | Florence | Rankin |
| Mar Jac Poultry MS LLC | Water - Pretreatment Renewal | Hattiesburg | Forrest |
| Margaret Myers, Johnny Myers Apartments | Water - State Operating Permit Renewal | Calhoun | Calhoun |
| Martin Transport Inc, Hattiesburg Truck Terminal | Water - State Operating Permit Renewal | Hattiesburg | Forrest |
| Masonite Corporation | Water - Pretreatment Renewal | Laurel | Jones |
| Masonite Corporation | Air - Title V Modification | Laurel | Jones |
| Maxie Sylvester, Big Oak Trailer Park | Water - NPDES Commercial Renewal | Beaumont | Perry |
| Mayersville POTW | Water - NPDES Minor Municipal Renewal | Mayersville | Issaquena |
| McComb POTW | Water - NPDES Major Municipal Modification | McComb | Pike |
| Memphis Communities LLC dba Buck Island MHC | Water - NPDES Commercial Renewal | Robinsonville | Tunica |
| Memphis Wealth Builders LLC, Chesterville Ridge | Water - State Operating Permit Renewal | Tupelo | Lee |
| Menasha Packaging Company LLC | Water - Pretreatment | Pelahatchie | Rankin |
| Menge Chevron LLC, Keith's Superstore Number 87 | Water - NPDES Commercial Renewal | Pass Christian | Harrison |
| Michael McFall, Ridgecrest Estates Mobile Home Park | Water - NPDES Commercial Renewal | Gulfport | Harrison |
| Mid South Baking Company LLC | Water - Pretreatment Renewal | Pelahatchie | Rankin |
| Minter City Water and Sewer District | Water - NPDES Minor Municipal Renewal | Minter City | Leflore |
| Mississippi Action For Progress Inc, Blanche Saucier Head Start | Water - NPDES Commercial Renewal | Saucier | Harrison |
| Mississippi Action for Progress Inc, Lexie Head Start, Early Head Start Center | Water - NPDES Commercial Renewal | Tylertown | Walthall |
| Mississippi Action for Progress Inc, Yale Headstart Center | Water - NPDES Commercial Renewal | Magnolia | Pike |
| Mississippi Department of Corrections, Quitman County Residential Treatment Facility | Water - NPDES Commercial Modification | Lambert | Quitman |
| Mississippi Department of Corrections, South Mississippi Correctional Institution | Water - NPDES Commercial, NPDES Minor Municipal Modification | Leakesville | Greene |
| Mississippi Department of Wildlife Fisheries and Parks, Lake Lincoln State Park | Water - NPDES Commercial Renewal | Wesson | Lincoln |
| Mississippi Department of Wildlife Fisheries and Parks, RV Campground, Calling Panther Lake | Water - State Operating Permit Renewal | Crystal Springs | Copiah |
| Mississippi Department of Wildlife Fisheries and Parks, Tippah County Lake | Water - NPDES Commercial Renewal | Falkner | Tippah |
| Mississippi Department of Wildlife Fisheries and Parks, Tishomingo State Park, Number 2 | Water - NPDES Commercial Renewal | Tishomingo | Tishomingo |
| Mississippi Department of Wildlife Fisheries and Parks, Wall Doxey State Park | Water - NPDES Commercial Renewal | Holly Springs | Marshall |
| Mississippi Department of Wildlife, Fisheries and Parks, Leroy Percy State Park | Water - NPDES Commercial Renewal | Hollandale | Washington |
| Mississippi Power Company, Plant Sweatt | Air - Title V Renewal | Meridian | Lauderdale |
| Mississippi Power Company, Plant Victor J Daniel | Air - Title V Minor Modification | Moss Point | Jackson |
| Mississippi State Elks Association, Mississippi Elks Kids Camp | Water - State Operating Permit Renewal | Hattiesburg | Forrest |
| Mississippi TanTec Leather Inc | Water - Pretreatment Renewal | Vicksburg | Warren |
| Mize POTW | Water - NPDES Minor Municipal Renewal | Mize | Smith |
| Monroe Gas Storage Company LLC, Monroe Gas Storage Project | Air - SMOP Modification | Amory | Monroe |
| Montague Aviation, LLC | Water - State Operating Permit Renewal | Inverness | Sunflower |
| Mount Olive POTW | Water - NPDES Minor Municipal Renewal | Mount Olive | Covington |
| Mount Olive Water Association, West View Subdivision | Water - NPDES Commercial Renewal | Bolton | Hinds |
| Mrs Teresa Rivers, Rivers Kuntry Katfish Inc | Water - State Operating Permit Renewal | Ellisville | Jones |
| Murtagh Flying Service Inc | Water - State Operating Permit | Lexington | Holmes |
| Natchez Trace Parkway, Jeff Busby Camper Park | Water - NPDES Commercial, NPDES Federal Minor Renewal | Ackerman | Choctaw |
| Natchez Trace Parkway, River Bend Comfort Station | Water - NPDES Commercial Renewal | Farmhaven | Madison |
| National Aeronautics and Space Administration, John C Stennis Space Center | Water - NPDES Minor Industrial Modification | Stennis Space Center | Hancock |
| National Aeronautics and Space Administration, John C Stennis Space Center | Air - Title V Modification | Stennis Space Center | Hancock |
| New Independence Missionary Baptist Church | Water - State Operating Permit Renewal | Coldwater | Tate |
| Newton POTW | Water - NPDES Minor Municipal Renewal | Newton | Newton |
| Nitrous Oxide Corporation | Water - Pretreatment | Yazoo City | Yazoo |
| North Carrollton POTW | Water - NPDES Minor Municipal Renewal | North Carrollton | Carroll |
| North Delta Ag Aviation LLC | Water - State Operating Permit Renewal | Sledge | Quitman |
| Nucor Steel Jackson Inc | Water - Pretreatment Renewal | Flowood | Rankin |
| Oakview Place Apartments | Water - NPDES Commercial Renewal | Corinth | Alcorn |
| Oasis Church of All Nations | Water - NPDES Commercial Renewal | Oxford | Lafayette |
| Oasis Haven Assisted Living | Water - NPDES Commercial Renewal | Terry | Hinds |
| Okhissa Lake Sewer District Wastewater Facility | Water - NPDES Minor Municipal Renewal | Meadville | Franklin |
| Old Natchez Trailer Park | Water - NPDES Commercial Renewal | Pontotoc | Pontotoc |
| Ole Miss Rentals LLC, Keystone Cottages | Water - NPDES Commercial Renewal | Oxford | Lafayette |
| Olin Winchester LLC | Water - Pretreatment Renewal | Oxford | Lafayette |
| Our Lady of Hope Inc | Water - NPDES Commercial Renewal | Osyka | Pike |
| Owls Head Alloys | Air - Construction Permit | West Point | Clay |
| Oxford, City of, Royal Oaks Wastewater Treatment Lagoon | Water - NPDES Commercial Renewal | Oxford | Lafayette |
| Oxford, City of, Thacker Heights Wastewater Treatment Lagoon | Water - NPDES Commercial Renewal | Oxford | Lafayette |
| Oxford, City of, Western Hills Wastewater Treatment Plant | Water - NPDES Commercial Renewal | Oxford | Lafayette |
| PG Technologies LLC | Water - Pretreatment Modification | Ellisville | Jones |
| Pachuta POTW | Water - NPDES Minor Municipal Renewal | Pachuta | Clarke |
| Pascagoula, City of, Criswell Street Water Treatment Plant | Water - NPDES Renewal | Pascagoula | Jackson |
| Pat Harrison Waterway District, Okatibbee Water Park | Water - State Operating Permit Renewal | Meridian | Lauderdale |
| Patrick Industries dba Baymont Composite South | Air - Title V Admin Mod | Iuka | Tishomingo |
| Pearl River County Board of Supervisors, Pearl River County Industrial Park | Water Quality - 401 Certification | Poplarville | Pearl River |
| Pearl River County Utility Authority, Neal Road POTW | Water - NPDES Major Municipal Renewal | Picayune | Pearl River |
| Pearl River County Utility Authority, Pearl River County Justice Facility | Water - NPDES Commercial Renewal | Poplarville | Pearl River |
| Pearl River County Utility Authority, Round Rock Subdivision | Water - NPDES Commercial Renewal | Picayune | Pearl River |
| Pearl River County Utility Authority, Tin Hill Subdivision | Water - State Operating Permit Renewal | Carriere | Pearl River |
| Peco Foods Inc, Canton Processing Plant | Water - Pretreatment Renewal | Canton | Madison |
| Pelahatchie POTW, West | Water - NPDES Minor Municipal Modification | Pelahatchie | Rankin |
| Perry County Schools, Runnelstown Attendance Center | Water - NPDES Commercial Renewal | Petal | Perry |
| Phibro RCB LLC | Air - SMOP Admin Mod | Natchez | Adams |
| Phoenix Nettleton MS I Industrial Investors LLC | Water - NPDES Minor Industrial Admin Mod | Nettleton | Monroe |
| Pike County Speedway LLC | Water - State Operating Permit Renewal | Magnolia | Pike |
| Pine Belt Regional Solid Waste Management Authority, Pine Belt Regional Landfill | Water - NPDES Storm Renewal | Runnelstown | Perry |
| Pine Belt Regional Solid Waste Management Authority, Pine Belt Regional Landfill | Water - Pretreatment Renewal | Runnelstown | Perry |
| Pine Grove M B Church | Water - State Operating Permit Renewal | Canton | Madison |
| Piney Woods Country Life School | Water - NPDES Commercial Renewal | Piney Woods | Rankin |
| Pitcock Meat Processing Inc | Water - State Operating Permit Renewal | Pope | Panola |
| Platte Chemical Co dba Loveland Products | Water - NPDES Storm Renewal | Greenville | Washington |
| Polychemie Inc | Air - SMOP Renewal | Pearlington | Hancock |
| Polychemie Inc | Water - NPDES Minor Industrial Renewal | Pearlington | Hancock |
| Pontotoc, City of, Activated Sludge Facility | Water - NPDES Major Municipal Admin Mod | Pontotoc | Pontotoc |
| Pontotoc, City of, Activated Sludge Facility | Water - NPDES Major Municipal Renewal | Pontotoc | Pontotoc |
| Potts Camp POTW, Northwest | Water - NPDES Minor Municipal Renewal | Potts Camp | Marshall |
| Prado Vista Real Estate Holdings, LLC, Prado Vista Development | Water Quality - 401 Certification | Ridgeland | Madison |
| Prairie Recycling Corporation | Solid Waste - Waste Tire Processor | Prairie | Monroe |
| Premier Foam LLC, Foam Fabrication Facility Number 2 | Air - SMOP | New Albany | Union |
| Prentiss County Schools, Hills Chapel School | Water - NPDES Commercial Renewal | Booneville | Prentiss |
| Prentiss County Schools, Thrasher High School | Water - NPDES Commercial Renewal | Booneville | Prentiss |
| Prestage Farms Mississippi Inc, Feed Mill | Water - State Operating Permit Renewal | West Point | Clay |
| Prestige Painting Belmont | Air - Title V Admin Mod | Belmont | Tishomingo |
| Prime Developers Inc, Southern Hills North | Water - NPDES Commercial Renewal | Meridian | Lauderdale |
| Producers Flying Inc, Yazoo City | Water - State Operating Permit Renewal | Yazoo City | Yazoo |
| Puckett Machinery Company, Puckett Rents Facility | Water - NPDES Minor Industrial Renewal | Biloxi | Harrison |
| Quad County Environmental Solutions, LLC - Quad County Landfill | Water - NPDES Storm Renewal | Byhalia | Marshall |
| Quad County Environmental Solutions, LLC - Quad County Landfill | Solid Waste - Mun Landfill Modification | Byhalia | Marshall |
| Quitman POTW | Water - NPDES Minor Municipal Renewal | Quitman | Clarke |
| Quitman Pellets LLC | Air - Title V Modification | Quitman | Clarke |
| R D Mobile Home Park | Water - NPDES Commercial Renewal | Barrontown | Forrest |
| Rain CII Carbon LLC | Water - NPDES Minor Industrial Renewal | Purvis | Lamar |
| Rankin County Rentals LLC | Water - State Operating Permit Renewal | Brandon | Rankin |
| Rankin County School District, McLaurin Attendance Center | Water - NPDES Commercial Renewal | Florence | Rankin |
| Rapid Oil Change Inc, Blue Sky Carwash | Water - NPDES Commercial Renewal | Flowood | Rankin |
| Raskin Transport LLC, dba Delta Village Mobile Home Park | Water - NPDES Commercial Renewal | Leland | Washington |
| Raworth and Harvel LLC, Country View Estates Mobile Home Park | Water - NPDES Commercial Renewal | Florence | Rankin |
| Rays Quality Meats LLC | Water - NPDES Minor Industrial Renewal | Petal | Forrest |
| Redditt Air Service Inc | Water - State Operating Permit Renewal | Skene | Bolivar |
| Redeemer Church | Water - State Operating Permit Renewal | Starkville | Oktibbeha |
| Resort Properties, LLC, Roundabout RV Resort | Water - State Operating Permit | Oxford | Lafayette |
| Restoration Community Fellowship Church | Water - NPDES Commercial Renewal | Florence | Rankin |
| Rimes Magnolia Landfill LLC | Solid Waste - Rubbish ADMIN | Magnolia | Pike |
| Rimes Magnolia Landfill LLC | Solid Waste - Rubbish ADMIN | Magnolia | Pike |
| Ripley POTW | Water - NPDES Major Municipal Renewal | Ripley | Tippah |
| Rosedale Flying Service Inc | Water - State Operating Permit Renewal | Rosedale | Bolivar |
| Rouse Management Company LLC, Richburg Road Apartments | Water - State Operating Permit Renewal | Hattiesburg | Lamar |
| Roy Lane, Chateau Lane Apartments | Water - NPDES Commercial Renewal | Starkville | Oktibbeha |
| Rudolph Foods Company Inc | Water - State Operating Permit Renewal | New Hebron | Lawrence |
| Russell Baptist Church | Water - NPDES Commercial Renewal | Meridian | Lauderdale |
| Russell Ridge Estates LLC | Water - NPDES Commercial Admin Mod | Meridian | Lauderdale |
| SASS, LLC, Catfish Country | Water - State Operating Permit Renewal | Hernando | Desoto |
| SHM Aqua Yacht LLC, dba Aqua Yacht Harbor | Water - State Operating Permit Renewal | Iuka | Tishomingo |
| SMHP LLC dba Smith Mobile Home Park | Water - NPDES Commercial Renewal | Clinton | Hinds |
| SMW Mfg, Inc | Water - Pretreatment Renewal | Oxford | Lafayette |
| SW Gaming LLC, dba Harlows Casino Resort and Spa | Water - NPDES Commercial Renewal | Greenville | Washington |
| Salem Heights Baptist Church | Water - State Operating Permit Renewal | Laurel | Jones |
| Sand Creek Wastewater Authority, Sand Creek POTW | Water - NPDES Major Municipal Modification | Saltillo | Lee |
| Sanderson Farms LLC, Collins Processing | Air - SMOP Renewal | Collins | Covington |
| Sanderson Farms LLC, Laurel Processing | Water - Pretreatment Renewal | Laurel | Jones |
| Sanderson Farms LLC, Processing Division Hazlehurst Processing | Water - NPDES Minor Industrial Renewal | Hazlehurst | Copiah |
| Sarah Hewlett, Taylor Grocery | Water - NPDES Commercial Renewal | Taylor | Lafayette |
| Sardis Lake Christian Camp | Water - NPDES Commercial Renewal | Batesville | Panola |
| Sardis POTW | Water - NPDES Minor Municipal Renewal | Sardis | Panola |
| Schlater Ag Air LLC | Water - State Operating Permit Renewal | Schlater | Leflore |
| Scranton Manufacturing Company Inc dba McLaughlin Family Companies Inc, NewWay | Air - SMOP Modification | Booneville | Prentiss |
| Scranton Manufacturing Company Inc dba McLaughlin Family Companies Inc, NewWay | Water - Pretreatment Modification | Booneville | Prentiss |
| Sebastopol Water Association | Water - NPDES Commercial Renewal | Sebastopol | Scott |
| Seminary POTW | Water - NPDES Minor Municipal Renewal | Seminary | Covington |
| Senatobia, City of, Back Acres Subdivision | Water - NPDES Commercial Renewal | Senatobia | Tate |
| Shelby POTW | Water - NPDES Minor Municipal Renewal | Shelby | Bolivar |
| Sidon POTW | Water - NPDES Minor Municipal Renewal | Sidon | Leflore |
| Sleepy Hollow RV Park Inc | Water - NPDES Commercial Renewal | Laurel | Jones |
| Smoco Holdings, LLC | Water - Pretreatment Renewal | Wiggins | Stone |
| Solero Technologies LLC | Water - Pretreatment Renewal | Water Valley | Yalobusha |
| South Haven Partnership LP, South Haven Townhouses | Water - NPDES Commercial Renewal | Vicksburg | Warren |
| South Meridian Apartments | Water - NPDES Commercial Renewal | Meridian | Lauderdale |
| Southeastern Timber Products LLC, Ackerman Plant | Water - NPDES Minor Industrial Renewal | Ackerman | Choctaw |
| Southern Cast Products Inc | Water - NPDES Minor Industrial Renewal | Meridian | Lauderdale |
| Southern Natural Gas Company LLC, Enterprise Compressor Station | Air - Title V Renewal | Enterprise | Clarke |
| Southern Natural Gas Company LLC, Louisville Compressor Station | Water - NPDES Minor Industrial Renewal | Louisville | Winston |
| Southern Oil Company, Fast Trac Number 7 | Water - NPDES Commercial Renewal | Perkinston | Stone |
| Speights Trailer Park | Water - NPDES Commercial Renewal | Columbia | Marion |
| Star View Mobile Home Park | Water - NPDES Commercial Renewal | Florence | Rankin |
| Starkville Wet N Wild LLC | Water - NPDES Commercial Renewal | Starkville | Oktibbeha |
| Stella Jones Corporation Durant | Air - Title V Minor Modification | Durant | Holmes |
| Sterling Specialty Chemicals US LLC | Air - SMOP Admin Mod | Aberdeen | Monroe |
| Sterling Specialty Chemicals US LLC | Water - Pretreatment Renewal | Aberdeen | Monroe |
| Stone County Utility Authority, South Stone County WWTF | Water - NPDES Minor Municipal Renewal | McHenry | Stone |
| Stone County Utility Authority, Wiggins Regional WWTF | Water - State Operating Permit Renewal | Wiggins | Stone |
| Summit at Oxford Commons, The | Water Quality - 401 Certification | Oxford | Lafayette |
| Sumrall POTW | Water - NPDES Minor Municipal Renewal | Sumrall | Lamar |
| Sunbelt Chemicals Inc | Water - Pretreatment Renewal | Gulfport | Harrison |
| Sunnyside Aero Inc | Water - State Operating Permit Renewal | Schlater | Leflore |
| Sunridge Management Group Inc, Pecan Ridge Apartments | Water - NPDES Commercial Renewal | Vicksburg | Warren |
| Symonds Water Association | Water - NPDES Minor Municipal Renewal | Symonds | Bolivar |
| T and D Construction Utility Company, Bridgewater Subdivision Phase Two | Water - NPDES Commercial Renewal | Ellisville | Jones |
| TVA Ackerman Combined Cycle | Air - Title V Renewal | Ackerman | Choctaw |
| TVA Southaven Combined Cycle Plant | Water - Pretreatment Renewal | Southaven | Desoto |
| Taber Extrusions LLC | Water - NPDES Minor Industrial Renewal | Gulfport | Harrison |
| Taylor Machine Works Inc, Plant 1, Plant 2, and Plant 3 | Air - SMOP Renewal | Louisville | Winston |
| Tennessee Gas Pipeline Company LLC, Batesville Compressor Station Number 63 | Air - Title V Renewal | Batesville | Panola |
| Tennessee Gas Pipeline Company LLC, New Albany Compressor Station Number 851 | Air - Title V Renewal | New Albany | Union |
| Tennessee Valley Authority, TVA, Kemper Combustion Turbine Plant | Water - NPDES Minor Industrial Renewal | Dekalb | Kemper |
| Terry POTW | Water - NPDES Minor Municipal Renewal | Terry | Hinds |
| Three Forks LLC dba Tallahatchie Flats | Water - NPDES Commercial Renewal | Greenwood | Leflore |
| Three Rivers Solid Waste Management Authority, Three Rivers Regional Landfill | Water - NPDES Storm Renewal | Pontotoc | Pontotoc |
| Three Rivers Solid Waste Management Authority, Three Rivers Regional Landfill | Water - Pretreatment Renewal | Pontotoc | Pontotoc |
| Timber Products Company | Air - SMOP Renewal | Corinth | Alcorn |
| Timberlane Utility LLC, Timberlane Subdivision | Water - NPDES Commercial Renewal | Tupelo | Pontotoc |
| Toomsuba Water Systems Inc, Plant Number 2 | Water - NPDES Minor Industrial Renewal | Toomsuba | Lauderdale |
| Toomsuba Water Systems Inc, Plant Number 3 | Water - NPDES Minor Industrial Renewal | Toomsuba | Lauderdale |
| Toro Energy Of Mississippi, LLC, Pecan Grove RNG Plant | Air - Construction Permit | Pass Christian | Harrison |
| TransAmerican Waste Central Landfill Inc, Central Landfill Facility | Water - NPDES Storm Renewal | McNeill | Pearl River |
| Trent Lott International Airport, Moss Point | Water Quality - 401 Certification | Moss Point | Jackson |
| Trulite Glass and Aluminum Solutions LLC | Air - Title V Renewal | Grenada | Grenada |
| Tunica Air Inc | Water - State Operating Permit Renewal | Tunica | Tunica |
| Tunica County Utility District, Dundee Facility | Water - NPDES Minor Municipal Renewal | Dundee | Tunica |
| Tunica County Utility District, Grand Casino | Water - NPDES Minor Municipal Renewal | Robinsonville | Tunica |
| Tunica Industrial Park | Water - NPDES Minor Industrial Renewal | Tunica | Tunica |
| Tupelo, City of, Wondura Class II Rubbish Landfill | Solid Waste - Rubbish Modification | Tupelo | Lee |
| Tutwiler POTW | Water - NPDES Minor Municipal Renewal | Tutwiler | Tallahatchie |
| US Army COE, Chickasaw Hill Recreation Area | Water - NPDES Commercial, NPDES Federal Minor Renewal | Enid | Yalobusha |
| US Army COE, Clear Creek Recreation Area | Water - NPDES Commercial Renewal | Oxford | Lafayette |
| US Army COE, DeWayne Hayes Recreation Area | Water - NPDES Commercial, NPDES Federal Minor Renewal | Columbus | Lowndes |
| US Army COE, Graysport Crossing Recreation Area | Water - NPDES Commercial, NPDES Federal Minor Renewal | Grenada | Grenada |
| US Army COE, Mobile District, Dredging Cadet Bayou | Water Quality - 401 Certification | Lakeshore | Hancock |
| US Army COE, Mobile District, Maintenance Dredging, Gulfport Harbor Navigation Project | Water Quality - 401 Certification | Gulfport | Harrison |
| US Army COE, Persimmon Hill Camp | Water - NPDES Commercial Renewal | Enid | Yalobusha |
| US Army COE, Riverview Recreation Area | Water - NPDES Commercial, NPDES Federal Minor Renewal | Enid | Yalobusha |
| US Army COE, Town Creek Recreation Area | Water - NPDES Commercial, NPDES Federal Minor Renewal | West Point | Clay |
| US Army COE, Wallace Creek Recreation Area | Water - NPDES Commercial, NPDES Federal Minor Renewal | Enid | Yalobusha |
| US Army COE, Water Valley Recreation Area | Water - NPDES Commercial, NPDES Federal Minor Renewal | Water Valley | Yalobusha |
| US Army COE, Waterway Management Center | Water - NPDES Commercial, NPDES Federal Minor Renewal | Columbus | Lowndes |
| US Forest Service, Davis Lake Recreation Area | Water - State Operating Permit Renewal | New Houlka | Chickasaw |
| USA Yeast Company LLC | Water - Pretreatment Renewal | Hattiesburg | Forrest |
| University of Mississippi Medical Center | Water - NPDES Minor Industrial Renewal | Jackson | Hinds |
| Utica POTW, South | Water - NPDES Minor Municipal Renewal | Utica | Hinds |
| Valley Racks Inc | Water - Pretreatment Renewal | Grenada | Grenada |
| Vicki Boargoub dba Family Meat Processing | Water - NPDES Minor Industrial Renewal | Sumrall | Lamar |
| Vicksburg Warren School District, Bovina Elementary School | Water - NPDES Commercial Renewal | Vicksburg | Warren |
| View Inc | Water - Pretreatment | Olive Branch | Desoto |
| Walker Hill Environmental Inc | Water - Pretreatment Renewal | Foxworth | Marion |
| Wash Mobile Home Park | Water - NPDES Commercial Renewal | Bogue Chitto | Lincoln |
| Waste Management of Mississippi Inc, Pine Ridge Sanitary Landfill and Recycling Center | Water - Pretreatment Renewal | Meridian | Lauderdale |
| Waste Management of Mississippi Inc, Pine Ridge Sanitary Landfill and Recycling Center | Water - NPDES Storm Renewal | Meridian | Lauderdale |
| Waste Management of Mississippi Inc, Plantation Oaks Landfill and Recycling Center, Natchez Hauling | Water - NPDES Storm Renewal | Sibley | Adams |
| Waste Management of Mississippi Inc, Prairie Bluff Landfill and Recycling Center | Water - Pretreatment Renewal | Houston | Chickasaw |
| Waste Management of Mississippi Inc, Prairie Bluff Landfill and Recycling Center | Water - NPDES Storm Renewal | Houston | Chickasaw |
| Waste Management of Tunica Landfill Inc | Water - NPDES Storm Renewal | Robinsonville | Tunica |
| Waste Management of Tunica Landfill Inc | Water - Pretreatment Renewal | Robinsonville | Tunica |
| Waste Water Solutions LLC, Pine Springs Estates Subdivision | Water - NPDES Commercial Renewal | Meridian | Lauderdale |
| Waste Water Solutions LLC, The Meadows Subdivision | Water - NPDES Commercial Renewal | Meridian | Lauderdale |
| Water Valley POTW | Water - NPDES Major Municipal | Water Valley | Yalobusha |
| West Madison Utility District | Water - NPDES Minor Municipal Renewal | Flora | Madison |
| West Tallahatchie Utilities Association Inc, Goose Pond Subdivision | Water - NPDES Commercial Renewal | Webb | Tallahatchie |
| Western Line School District, Riverside High School | Water - NPDES Commercial Renewal | Avon | Washington |
| Weyerhaeuser NR Company, Bruce Facility | Air - Title V Renewal | Bruce | Calhoun |
| Weyerhaeuser NR Company, Philadelphia Facility | Water - NPDES Minor Industrial Renewal | Philadelphia | Neshoba |
| Wheeler Grove Baptist Church | Water - State Operating Permit Renewal | Corinth | Alcorn |
| Williams Equipment Company, Cleveland | Water - State Operating Permit | Cleveland | Bolivar |
| Williams Equipment Company, Oxford | Water - State Operating Permit | Oxford | Lafayette |
| Williams Equipment and Supply Company Byhalia | Water - State Operating Permit | Byhalia | Marshall |
| Williams Equipment and Supply Company, Richland | Water - State Operating Permit | Richland | Rankin |
| Winston Plywood and Veneer LLC | Air - Title V Renewal | Louisville | Winston |
| Wis Pak of Hattiesburg, LLC | Water - Pretreatment Renewal | Hattiesburg | Forrest |
| Yazoo County School District, Yazoo County Middle and High School Campus | Water - NPDES Commercial Renewal | Yazoo City | Yazoo |
| Yazoo Mississippi Delta Levee Board, McKinney Bayou Shop | Water - State Operating Permit Renewal | Tunica | Tunica |
| Yokohama Tire Manufacturing Mississippi LLC | Air - Title V Renewal | West Point | Clay |
| Yokohama Tire Manufacturing Mississippi LLC | Water - Pretreatment Renewal | West Point | Clay |